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A power drill is an easy-to-use tool ideal for a variety of construction projects and home repairs. Learn more about wood drill bits, masonry drill bit sets, auger bits and where to use them for greater quality and efficiency on the job.

For basic repair jobs around the house, consider investing in a drill bit set or a driver bit set, which comes with various bit types and sizes for multi-purpose use. If you work with one type of material regularly, purchasing a set of bits purpose-built for your specific tasks is an efficient and easy way to get the job done.

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Assembling a toolbox to stay prepared for any job is essential for DIYers and professionals alike. This makes having a variety of drill bits to tackle specific tasks is crucial. Find out which bit types you’ll need for which jobs with Ace’s handy guide.

What’s more, Ace also offers a selection of screwdriver bits to help you complete tasks that call for a little more elbow grease where a power tool may not fit.

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BACKGROUNDUnderstanding HIV dynamics across the human body is important for cure efforts. This goal has been hampered by technical difficulties and the challenge of obtaining fresh tissues.METHODSThis observational study evaluated 6 individuals with HIV (n = 4 with viral suppression using antiretroviral [ART] therapy; n = 2 with rebound viremia after stopping ART), who provided serial blood samples before death and their bodies for rapid autopsy. HIV reservoirs were characterized by digital droplet PCR, single-genome amplification, and sequencing of full-length (FL) envelope HIV. Phylogeographic methods were used to reconstruct HIV spread, and generalized linear models were tested for viral factors associated with dispersal.RESULTSAcross participants, HIV DNA levels varied from approximately 0 to 659 copies/106 cells (IQR: 22.9-126.5). A total of 605 intact FL env sequences were recovered in antemortem blood cells and across 28 tissues (IQR: 5-9). Sequence analysis showed (a) the emergence of large, identical, intact HIV RNA populations in blood after cessation of therapy, which repopulated tissues throughout the body; (b) that multiple sites acted as hubs for HIV dissemination but that blood and lymphoid tissues were the main source; (c) that viral exchanges occurred within brain areas and across the blood-brain barrier; and (d) that migration was associated with low HIV divergence between sites and greater diversity at the recipient site.CONCLUSIONHIV reservoirs persisted in all deep tissues, and blood was the main source of dispersal. This may explain why eliminating HIV susceptibility in circulating T cells via bone marrow transplants allowed some individuals with HIV to experience therapy-free remission, even though deeper tissue reservoirs were not targeted.TRIAL REGISTRATIONNot applicable.FUNDINGNIH grants P01 AI31385, P30 AI036214, AI131971-01, AI120009AI036214, HD094646, AI027763, AI134295, and AI68636.

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Reliable tools are must-haves no matter what you’re working on. This is why Ace offers a selection of wood and metal drill bit sets from reputable brands to fit your cordless and electric drills. Shop drill bits from DeWalt, Milwaukee, Irwin and Ace brand tools to find the right selection to meet your needs.

Reference the chart above to discover which drill bits are right for your needs, then shop drill bits and sets near you at Ace Hardware. Whether you’re looking for countersink bits, drill chucks or entire sets of multi-purpose bits, find everything you want in one place.

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Not all drill bits can go through metal. Look for drill bits for metal like wire gauge, titanium, cobalt or Brad point to let you complete even the toughest jobs with ease. What’s more, carbide-tipped drill bits also work well as concrete drill bits.